Bassoon 抗体 (AA 786-1041)
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- 抗原 See all Bassoon (BSN) 抗体
- Bassoon (BSN)
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抗原表位
- AA 786-1041
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Bassoon antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 特异性
- Detects ~420 kDa. Multiple isoforms can be detected.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein A Purified
- 免疫原
- NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
- Top Product
- Discover our top product BSN Primary Antibody
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- 应用备注
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- WB (1:1000)
- IHC (1:400)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN863198 was sufficient for detection of Bassoon in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- Bassoon (BSN)
- 别名
- Bassoon (BSN 产品)
- 别名
- Znf231 antibody, ZNF231 antibody, bassoon antibody, bassoon (presynaptic cytomatrix protein) antibody, bassoon presynaptic cytomatrix protein antibody, Bsn antibody, BSN antibody
- 背景
- Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors (1).
- 基因ID
- 8927
- NCBI登录号
- NP_003449
- UniProt
- Q9UPA5
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