Piccolo 抗体
-
- 抗原 See all Piccolo (PIC) products
- Piccolo (PIC)
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Piccolo antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Detects ~550 kDa. No cross-reactivity to Bassoon.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein A Purified
- 免疫原
- Recombinant Full length Protein, BC001304.1
-
-
- 应用备注
-
- WB (1:1000)
- IHC (1:400)
- optimal dilutions for assays should be determined by the user.
- 说明
-
1 μg/ml of ABIN863197 was sufficient for detection of Piccolo in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
-
- 抗原
- Piccolo (PIC)
- 别名
- Piccolo (PIC 产品)
- 背景
- Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains (1, 2). In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) (3). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 (2).
- 基因ID
- 27445
- NCBI登录号
- NP_055325
- UniProt
- Q9Y6V0
-