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Piccolo 抗体

PIC 适用: 小鼠 WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 6H9-B6 unconjugated
产品编号 ABIN863105
发货至: 中国
  • 抗原 See all Piccolo (PIC) products
    Piccolo (PIC)
    适用
    • 24
    • 15
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 20
    • 13
    • 1
    • 1
    小鼠
    克隆类型
    • 22
    • 13
    单克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Piccolo antibody is un-conjugated
    应用范围
    • 30
    • 16
    • 15
    • 11
    • 9
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Detects ~550 kDa. No cross-reactivity to Bassoon.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Full length recombinant protein (GenBank ID: BC001304.1)
    克隆位点
    6H9-B6
    亚型
    IgG2b kappa
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN863104 was sufficient for detection of Piccolo in 20 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    Piccolo (PIC)
    别名
    Piccolo (PIC 产品)
    背景
    Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains (1, 2). In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) (3). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 (2).
    基因ID
    26875
    NCBI登录号
    NP_001104266
    UniProt
    Q9QYX7
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