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Integrin beta 3 抗体

Name: Integrin beta 3 抗体
Brand: antibodies-online
SKU: ABIN810075
Availability: OutOfStock

ITGB3 适用: 人, Non-Human Primate WB, FACS, IHC (fro) 宿主: 小鼠 Monoclonal VIPL2 unconjugated

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD61 (VIPL2) purified antibody (concentration in sample 3 μg/mL, GAM APC). (Integrin beta 3 抗体)

FACS

Separation of human CD61 positive thrombocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human CD61 (VIPL2) purified antibody (concentration in sample 3 μg/mL, GAM APC). (Integrin beta 3 抗体)

FACS

2 images

(6 references)

产品编号 ABIN810075

发货至: 中国

Datasheet as PDF

抗原 See all Integrin beta 3 (ITGB3) 抗体

Integrin beta 3 (ITGB3)
适用
180

94

58

14

13

12

11

9

7

7

4

2

2

2

1

1

1

1
人, Non-Human Primate
宿主
124

59

11

2
小鼠
Compatible Secondaries
克隆类型
120

74
单克隆
标记
98

17

12

11

7

5

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This Integrin beta 3 antibody is un-conjugated
应用范围
125

79

53

53

27

25

23

20

15

13

12

5

5

3

3

3

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

特异性

The mouse monoclonal antibody VIPL2 recognizes an extracellular epitope of CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.

交叉反应（详细）

Human, Non-Human Primates

纯化方法

Purified by protein-A affinity chromatography.

纯度

> 95 % (by SDS-PAGE)

克隆位点

VIPL2

亚型

IgG1 kappa

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anti-Integrin beta 3 (ITGB3) (AA 27-120) antibody
ITGB3 适用: 人, 小鼠 WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 134-376) antibody
ITGB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) antibody
ITGB3 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 27-179) antibody
ITGB3 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 3E8A6 unconjugated

anti-Integrin beta 3 (ITGB3) (AA 385-490) antibody
ITGB3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGB3-2145 unconjugated

anti-Integrin beta 3 (ITGB3) antibody (FITC)
ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 FITC

anti-Integrin beta 3 (ITGB3) antibody (PerCP)
ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 PerCP

anti-Integrin beta 3 (ITGB3) (AA 610-718) antibody
ITGB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 734-760) antibody
ITGB3 适用: 人 WB, FACS, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 135-377) antibody
ITGB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Flow cytometry: Recommended dilution: 1-4 μg/mL.

限制

仅限研究用
浓度

1 mg/mL

缓冲液

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.

储存条件

4 °C

储存方法

Store at 2-8°C. Do not freeze.
Barrett, Dai, Gamberg, Gallant, Grant: "Circulating CD14-CD36+ peripheral blood mononuclear cells constitutively produce interleukin-10." in: Journal of leukocyte biology, Vol. 82, Issue 1, pp. 152-60, (2007) (PubMed).

Mondal, Williams, Ali, Eilers, Agrawal: "The HIV-1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells." in: Experimental biology and medicine (Maywood, N.J.), Vol. 230, Issue 9, pp. 631-44, (2005) (PubMed).

Williams, Mondal, Agrawal: "The HIV-1 Tat protein enhances megakaryocytic commitment of K562 cells by facilitating CREB transcription factor coactivation by CBP." in: Experimental biology and medicine (Maywood, N.J.), Vol. 230, Issue 11, pp. 872-84, (2005) (PubMed).

Roberts, Woods, Dale, Van Der Sluijs, Norman: "Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins." in: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1505-15, (2004) (PubMed).

Ciarlet, Crawford, Cheng, Blutt, Rice, Bergelson, Estes: "VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment." in: Journal of virology, Vol. 76, Issue 3, pp. 1109-23, (2002) (PubMed).

Dzionek, Fuchs, Schmidt, Cremer, Zysk, Miltenyi, Buck, Schmitz: "BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6037-46, (2000) (PubMed).
抗原

Integrin beta 3 (ITGB3)

别名

CD61 (ITGB3 产品)

别名

BDPLT16 antibody, BDPLT2 antibody, CD61 antibody, GP3A antibody, GPIIIa antibody, GT antibody, INGRB3 antibody, integrin antibody, INTB3 antibody, GPIIIA antibody, cd61 antibody, gp3a antibody, itgb3 antibody, itgb3.2 antibody, itgb3.1 antibody, integrin subunit beta 3 antibody, integrin beta 3 antibody, integrin subunit beta 3 L homeolog antibody, integrin beta 3a antibody, integrin beta 3b antibody, ITGB3 antibody, Itgb3 antibody, itgb3.L antibody, itgb3a antibody, itgb3b antibody

背景

Integrin subunit beta 3,CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.,integrin beta 3, ITGB3, GP3A

基因ID

3690

UniProt

P05106

途径

Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex