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IRS2 抗体 (pSer731)

IRS2 适用: 人, 小鼠, 大鼠 FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN801468
发货至: 中国
  • 抗原 See all IRS2 抗体
    IRS2 (Insulin Receptor Substrate 2 (IRS2))
    抗原表位
    • 16
    • 16
    • 10
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer731
    适用
    • 76
    • 43
    • 29
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 77
    克隆类型
    • 77
    多克隆
    标记
    • 22
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRS2 antibody is un-conjugated
    应用范围
    • 38
    • 36
    • 30
    • 27
    • 18
    • 10
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human IRS-2 around the phosphorylation site of Ser731
    亚型
    IgG
    Top Product
    Discover our top product IRS2 Primary Antibody
  • 应用备注
    WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    IRS2 (Insulin Receptor Substrate 2 (IRS2))
    别名
    Irs-2 (IRS2 产品)
    别名
    IRS2 antibody, si:dkeyp-24d6.1 antibody, IRS-2 antibody, 4PS antibody, Irs-2 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 2a antibody, insulin receptor substrate 2b antibody, IRS2 antibody, irs2a antibody, irs2b antibody, Irs2 antibody
    背景

    Synonyms: Insulin Receptor Substrate 2, IRS 2, IRS2.

    Background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions, however, the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

    基因ID
    8660
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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