Seladin 1 抗体
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- 抗原 See all Seladin 1 (DHCR24) 抗体
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Seladin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, Pig, 大鼠
- 预测反应
- Human,Dog,Cow,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Seladin 1
- 亚型
- IgG
- Top Product
- Discover our top product DHCR24 Primary Antibody
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anti-24-Dehydrocholesterol Reductase (DHCR24) antibody
DHCR24 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 227-516) antibodyDHCR24 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 38-87) antibodyDHCR24 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 431-480) antibodyDHCR24 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 57-87), (N-Term) antibodyDHCR24 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB17628 unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- 别名
- Seladin 1 (DHCR24 产品)
- 别名
- MGC82737 antibody, zgc:101638 antibody, DCE antibody, Nbla03646 antibody, SELADIN1 antibody, seladin-1 antibody, 2310076D10Rik antibody, 5830417J06Rik antibody, mKIAA0018 antibody, 24-dehydrocholesterol reductase antibody, 24-dehydrocholesterol reductase S homeolog antibody, delta(24)-sterol reductase antibody, DHCR24 antibody, dhcr24.S antibody, dhcr24 antibody, LOC5575872 antibody, CpipJ_CPIJ000670 antibody, Dhcr24 antibody
- 背景
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Synonyms: Seladin1, Seladin-1, DHCR24, 24 dehydrocholesterol reductase, 3-beta-hydroxysterol delta-24-reductase, DCE, Desmosterol to cholesterol enzyme, Diminuto dwarf1 homolog, SELADIN1, Selective AD indicator 1, Selective Alzheimer's Disease Indicator 1.
Background: Seladin 1 is highly expressed in brain, adrenal tissues and adrenal tumours, where this enzyme catalyzes the reduction of the delta-24 double bond of sterol intermediates such as desmosterol, during cholesterol biosynthesis. In addition, Seladin 1 has an anti-apoptotic function by reducing caspase 3 activity during oxidative stress-induced apoptosis and protecting cells against amyloid-beta peptide-induced apoptosis. Several studies have identified a reduction in expression levels of this enzyme in brain regions affected by Alzheimer's disease (hippocampus and the subventricular zone).
- 基因ID
- 1718
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