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GRIN2B 抗体 (pTyr1336)

GRIN2B 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN801228
发货至: 中国
  • 抗原 See all GRIN2B 抗体
    GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
    抗原表位
    • 30
    • 26
    • 23
    • 21
    • 21
    • 19
    • 16
    • 10
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    • 5
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    pTyr1336
    适用
    • 189
    • 170
    • 145
    • 25
    • 22
    • 19
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    大鼠, 小鼠
    宿主
    • 197
    • 35
    • 1
    克隆类型
    • 199
    • 34
    多克隆
    标记
    • 97
    • 11
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
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    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GRIN2B antibody is un-conjugated
    应用范围
    • 194
    • 64
    • 64
    • 63
    • 45
    • 39
    • 25
    • 23
    • 23
    • 18
    • 18
    • 10
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This phosphorylation site is homologous to that of Tyr1336 in Mouse and Rat.
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1336
    亚型
    IgG
    Top Product
    Discover our top product GRIN2B Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
    别名
    NMDAR2B (GRIN2B 产品)
    别名
    NMDAR2B antibody, GluN2B antibody, MRD6 antibody, NR2B antibody, hNR3 antibody, nmdar2b antibody, nr2b antibody, AW490526 antibody, Nmdar2b antibody, glutamate ionotropic receptor NMDA type subunit 2B antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog antibody, glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody, GRIN2B antibody, Grin2b antibody, grin2b.L antibody
    背景

    Synonyms: MRD6, NR2B, hNR3, GluN2B, NMDAR2B, Glutamate receptor ionotropic, NMDA 2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NR3, GRIN2B

    Background: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).

    基因ID
    2904
    UniProt
    Q13224
    途径
    Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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