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PLCz1 抗体 (AA 351-450)

PLCz1 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN801183
发货至: 中国
  • 抗原 See all PLCz1 抗体
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    抗原表位
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    适用
    • 20
    • 14
    • 4
    大鼠
    宿主
    • 33
    • 2
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLCz1 antibody is un-conjugated
    应用范围
    • 12
    • 12
    • 11
    • 10
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PLCZ1
    亚型
    IgG
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    别名
    PLCZ1 (PLCz1 产品)
    别名
    PLC-zeta-1 antibody, PLCZ1 antibody, 1700041H07Rik antibody, PLCzeta antibody, NYD-SP27 antibody, PLCZ antibody, phospholipase C zeta 1 antibody, phospholipase C, zeta 1 antibody, PLCZ1 antibody, Plcz1 antibody
    背景

    Synonyms: PLCzeta, NYD-SP27, PLC-zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, Phosphoinositide phospholipase C-zeta-1, Phospholipase C-zeta-1, Testis-development protein NYD-SP27, PLCZ1, PLCZ1_HUMAN

    Background: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

    基因ID
    89869
    UniProt
    Q86YW0
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