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PDGFRA 抗体 (AA 1035-1053)
PDGFRA
适用: 人, 小鼠, 大鼠, 小鸡, 非洲爪蟾
WB, IHC (p), IP
宿主: 兔
Polyclonal
unconjugated
PDGFRA抗体详情
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抗原
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PDGFRA
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
抗原表位
All epitopes for PDGFRA 抗体
AA 1035-1053
适用
All reactivities for PDGFRA 抗体
人, 小鼠, 大鼠, 小鸡, 非洲爪蟾
宿主
All hosts for PDGFRA 抗体
兔
克隆类型
All clonalities for PDGFRA 抗体
多克隆
标记
All conjugates for PDGFRA 抗体
This PDGFRA antibody is un-conjugated
应用范围
All applications for PDGFRA 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
序列
C-GKRNRHSSQT SEESAIETG Remarks: Antigen Modificati on: Amino acids 1035-1053
特异性
Recognizes Human PDGF Receptor Type A, doublet, Mr 150/170 kDa.
交叉反应 (详细)
Species reactivity (expected):Chicken, Frog, Mouse, Rat, Zebrafish. Species reactivity (tested):Human.
纯化方法
Immunoaffinity Chromatography
免疫原
Synthetic peptide KLH-conjugated corresponding to amino acids 1035-1053 of Human PDGF.
亚型
IgG
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
0.2 M Tris-Glycine, pH 7.4 containing 0.12 M Sodium Chloride and 0.05 % Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
PDGFRA目标详情
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抗原
PDGFRA
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
别名
CD140a / PDGFRA (PDGFRA 产品 )
别名
AI115593 antibody, CD140a antibody, Pdgfr-2 antibody, APDGFR antibody, PDGFACE antibody, CD140A antibody, PDGFR-2 antibody, PDGFR2 antibody, RHEPDGFRA antibody, PDGFR antibody, PDGFR-A antibody, platelet derived growth factor receptor alpha antibody, platelet derived growth factor receptor, alpha polypeptide antibody, platelet-derived growth factor receptor, alpha polypeptide L homeolog antibody, platelet-derived growth factor receptor, alpha polypeptide antibody, PDGFRA antibody, Pdgfra antibody, pdgfra.L antibody
背景
Platelet-derived Growth Factor Receptor Alpha (PDGFR alpha), a member of the a PDGF Receptor tyrosine kinase family, is a mediator of the biological actions of platelet-derived growth factor (PDGF). PDGF binding to PDGF receptors result in stimulation of cell growth, chemotaxis, and cell shape changes. Unlike PDGFR beta, PDGFR alpha can bind to both PDGF subunits. PDGFR alpha has been implicated in the development of spina bifida. In various mouse models, deregulated PDGFR alpha expression was found to result in congenital neural tube defects. In humans, various PDGFRA promoter haplotypes have been associated with neural tube defects.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha
基因ID
5156
NCBI登录号
NP_006197
途径
RTK signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Platelet-derived growth Factor Receptor Signaling
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