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MAPT 抗体

MAPT 适用: 人, 大鼠, 小鼠, Cow, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783852
发货至: 中国
  • 抗原 See all MAPT 抗体
    MAPT (Microtubule-Associated Protein tau (MAPT))
    适用
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    人, 大鼠, 小鼠, Cow, 小鸡
    宿主
    • 188
    • 18
    • 6
    克隆类型
    • 188
    • 24
    多克隆
    标记
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    This MAPT antibody is un-conjugated
    应用范围
    • 182
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    Western Blotting (WB)
    特异性
    This antibody recognizes mainly the truncated Tau (~30 kDa) in samples from human, mouse and rat origins. Other isoforms of Tau at 35 kDa, 60 kDa and 80 kDa can also be recognized.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat, chicken, bovine
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic peptide surrounding amino acid 395 of rat Tau
    Top Product
    Discover our top product MAPT Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
  • 抗原
    MAPT (Microtubule-Associated Protein tau (MAPT))
    别名
    MAPT / tau (MAPT 产品)
    别名
    DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, AI413597 antibody, AW045860 antibody, Mtapt antibody, Tau antibody, RNPTAU antibody, pTau antibody, tau antibody, xtp antibody, MAPT antibody, PHF-tau antibody, slc6a6 antibody, taut antibody, wu:fc26e12 antibody, microtubule associated protein tau antibody, microtubule-associated protein tau antibody, microtubule associated protein tau S homeolog antibody, Microtubule-associated protein tau antibody, solute carrier family 6 (neurotransmitter transporter), member 6b antibody, MAPT antibody, Mapt antibody, mapt.S antibody, LOC5580230 antibody, CpipJ_CPIJ013260 antibody, tau antibody, slc6a6b antibody
    背景
    Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheimer's disease. Hyperphosphorylation of Tau is thought to be the critical event leading to the assembly of PHF. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK3. This presents the possibility that miscues in GSK3 signaling contribute to the onset of Alzheimer's disease.Synonyms: MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau
    基因ID
    4137
    NCBI登录号
    NP_001116538
    UniProt
    P10636
    途径
    MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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