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- 抗原 See all TMEM59 抗体
- TMEM59 (Transmembrane Protein 59 (TMEM59))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TMEM59 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects TMEM59 at N-term.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 16 amino acid peptide near amino terminus of human TMEM59
- Top Product
- Discover our top product TMEM59 Primary Antibody
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anti-Transmembrane Protein 59 (TMEM59) antibody
TMEM59 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59 (TMEM59) (AA 59-201) antibodyTMEM59 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59 (TMEM59) (AA 36-230) antibodyTMEM59 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- TMEM59 (Transmembrane Protein 59 (TMEM59))
- 别名
- TMEM59 (TMEM59 产品)
- 别名
- Tmem59 antibody, C1orf8 antibody, HSPC001 antibody, 1110001M20Rik antibody, 3110046P06Rik antibody, AI256529 antibody, D4Ertd20e antibody, MTDCF1 antibody, ORF18 antibody, transmembrane protein 59 antibody, tmem59 antibody, Tmem59 antibody, TMEM59 antibody
- 背景
- Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.Synonyms: C1orf8, HSPC001, Liver membrane-bound protein, Transmembrane protein 59
- 基因ID
- 9528
- NCBI登录号
- NP_004863
- UniProt
- Q9BXS4
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