SYNPO2 抗体 (N-Term)
Quick Overview for SYNPO2 抗体 (N-Term) (ABIN783775)
抗原
See all SYNPO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects SYNPO2 at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 20 amino acid peptide near the amino terminus of human SYNPO2
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anti-Synaptopodin 2 (SYNPO2) (Internal Region) antibody
SYNPO2 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptopodin 2 (SYNPO2) (AA 1-300) antibodySYNPO2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptopodin 2 (SYNPO2) (C-Term) antibodySYNPO2 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- SYNPO2 (Synaptopodin 2 (SYNPO2))
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别名
- SYNPO2
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背景
- SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of signaling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that down-regulation of SYNPO2 reduces the invasiveness and motility of prostate cancer cells.
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基因ID
- 171024
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NCBI登录号
- NP_001122405
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UniProt
- Q9UMS6
抗原
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