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NALP8 抗体 (N-Term)

NLRP8 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783713
发货至: 中国
  • 抗原 See all NALP8 (NLRP8) 抗体
    NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))
    抗原表位
    • 2
    • 1
    • 1
    N-Term
    适用
    宿主
    • 2
    • 1
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This NALP8 antibody is un-conjugated
    应用范围
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects NALP8 at N-term. This antibody is predicted to not cross-react with other NALP family members.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography purified via peptide column
    免疫原
    16 amino acid peptide near the amino terminus of Human NALP8
    Top Product
    Discover our top product NLRP8 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))
    别名
    NALP8 (NLRP8 产品)
    别名
    CLR19.2 antibody, NALP8 antibody, NOD16 antibody, PAN4 antibody, NLR family pyrin domain containing 8 antibody, NLRP8 antibody
    背景
    NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.Synonyms: LRR and PYD domains-containing protein 8, NACHT, NLRP8, NOD16, PAN4, PYRIN and NACHT-containing protein 4
    基因ID
    126205
    NCBI登录号
    NP_789781
    UniProt
    Q86W28
    途径
    Inflammasome
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