BNAR antibody, C9orf143 antibody, C9orf145 antibody, C9orf154 antibody, MOTA antibody, TILRR antibody, TRIGNO2 antibody, RGD1306981 antibody, BC037594 antibody, D430009N09 antibody, D630008K06 antibody, eye antibody, eyes2 antibody, heb antibody, qbrick antibody, FRAS1 related extracellular matrix 1 antibody, Fras1 related extracellular matrix 1 antibody, Fras1 related extracellular matrix protein 1 antibody, FREM1 antibody, Frem1 antibody
背景
FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.Synonyms: C9orf143, C9orf145, C9orf154, FRAS1-related extracellular matrix protein 1, Protein QBRICK