Transportin 3 抗体 (N-Term)
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- 抗原 See all Transportin 3 (TNPO3) 抗体
- Transportin 3 (TNPO3)
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Transportin 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects Transportin-3 (TNPO3) at N-term.
- 交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 18 amino acid peptide from near the amino terminus of human TNPO3
- Top Product
- Discover our top product TNPO3 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- Transportin 3 (TNPO3)
- 别名
- Transportin-3 (TNPO3) (TNPO3 产品)
- 别名
- zgc:55409 antibody, tnpo3 antibody, MGC82948 antibody, TNPO3 antibody, DKFZp459J2330 antibody, IPO12 antibody, MTR10A antibody, TRN-SR antibody, TRN-SR2 antibody, TRNSR antibody, 5730544L10Rik antibody, C430013M08Rik antibody, C81142 antibody, D6Ertd313e antibody, Trn-SR antibody, mKIAA4133 antibody, transportin 3 antibody, transportin 3 S homeolog antibody, transportin-SR antibody, tnpo3 antibody, TNPO3 antibody, tnpo3.S antibody, Bm1_43850 antibody, LOAG_04608 antibody, Tnpo3 antibody
- 背景
- TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated. More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.Synonyms: IPO12, Imp12, Importin-12, TRN-SR, Transportin-SR
- 基因ID
- 23534
- NCBI登录号
- NP_001177957
- UniProt
- Q9Y5L0
- 途径
- Protein targeting to Nucleus
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