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CCDC141 抗体 (N-Term)

CCDC141 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783520
发货至: 中国
  • 抗原 See all CCDC141 抗体
    CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))
    抗原表位
    • 14
    • 8
    • 1
    • 1
    • 1
    N-Term
    适用
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    This CCDC141 antibody is un-conjugated
    应用范围
    • 17
    • 12
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects CCDC141 at N-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid peptide near the amino terminus of human CCDC141
    Top Product
    Discover our top product CCDC141 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))
    别名
    CCDC141 (CCDC141 产品)
    别名
    CAMDI antibody, 2610301F02Rik antibody, ENSMUSG00000075261 antibody, coiled-coil domain containing 141 antibody, CCDC141 antibody, Ccdc141 antibody
    背景
    Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development. At least four isoforms of CCDC141 are known to exist.Synonyms: Coiled-coil domain-containing protein 141
    基因ID
    285025
    NCBI登录号
    NP_775919
    UniProt
    Q6ZP82
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