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- 抗原 See all RASSF10 products
- RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RASSF10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects RASSF10 at N-term. RASSF10 antibody will not cross-react with other RAS association domain-containing family members.
- 交叉反应 (详细)
- Species reactivity (tested):Human
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 17 amino acid peptide near the amino terminus of human RASSF10
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis." in: Molecular biology of the cell, Vol. 19, Issue 4, pp. 1772-82, (2008) (PubMed).
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RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis." in: Molecular biology of the cell, Vol. 19, Issue 4, pp. 1772-82, (2008) (PubMed).
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- 抗原
- RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))
- 别名
- RASSF10 (RASSF10 产品)
- 别名
- 4632411J06Rik antibody, Ras association domain family member 10 antibody, Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 antibody, RASSF10 antibody, Rassf10 antibody
- 背景
- RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.Synonyms: Ras association domain-containing protein 10
- 基因ID
- 644943
- NCBI登录号
- NP_001073990
- UniProt
- A6NK89
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