VASH1 抗体 (C-Term)
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- 抗原 See all VASH1 抗体
- VASH1 (Vasohibin 1 (VASH1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VASH1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detctes Vasohibin-1 / VASH1 at C-term. VASH1 antibody is predicted to not cross-react with other vasohibin protein family members. At least two isoforms are known to exist, this antibody will recognize only the long isoform.
- 交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 19 amino acid peptide near the carboxy terminus of human VASH1
- Top Product
- Discover our top product VASH1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- VASH1 (Vasohibin 1 (VASH1))
- 别名
- Vasohibin-1 / VASH1 (VASH1 产品)
- 别名
- KIAA1036 antibody, AI834978 antibody, D930046M13Rik antibody, G630009D10Rik antibody, RGD1564082 antibody, vasohibin 1 antibody, VASH1 antibody, vash1 antibody, Vash1 antibody
- 背景
- VASH1 was originally identified as an endothelium-derived vascular endothelial growth factor (VEGF)-inducible angiogenesis inhibitor that acts in a negative feedback manner. VASH1 mRNA is expressed brain, heart, kidney and placenta in the adult, with robust expression in various organs during embryonic development. VASH1 expression in tumor cells and tumor vasculature is silenced by methylation by increased expression of Zeste homolog 2 (EZH2). The increase of EZH2 expression is induced by VEGF stimulation, leading to poor clinical prognosis. Recombinant adenovirus expressing VASH prevented tumor angiogenesis and inhibited tumor growth, suggesting that it may be a potentially valuable antitumor therapy in the clinic.Synonyms: KIAA1036, VASH
- 基因ID
- 22846
- NCBI登录号
- NP_055724
- UniProt
- Q7L8A9
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