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ZNF219 抗体 (N-Term)

ZNF219 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783427
发货至: 中国
  • 抗原 See all ZNF219 抗体
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    抗原表位
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 10
    克隆类型
    • 10
    多克隆
    标记
    • 10
    This ZNF219 antibody is un-conjugated
    应用范围
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects ZNF219 at N-term. At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid peptide near the amino terminus of human ZFP219
    Top Product
    Discover our top product ZNF219 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    别名
    ZNF219 (ZNF219 产品)
    背景
    ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.Synonyms: Zinc finger protein 219
    基因ID
    51222
    NCBI登录号
    NP_001095142
    UniProt
    Q9P2Y4
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