CD2F-10 antibody, CD2F10 antibody, CD84-H1 antibody, CD84H1 antibody, SF2001 antibody, 2310026I04Rik antibody, AI462096 antibody, Cd2f10 antibody, SLAM family member 9 antibody, SLAMF9 antibody, Slamf9 antibody
背景
The SLAM (signalling lymphocyte activation molecule) family is a novel group of receptors on T cells in modulating the immune response. SLAMF9, also known as CD2F-10 or CD84 homolog, is a 289 amino acid type I transmembrane protein that shares 58 % identity with the mouse protein. The SLAMF9 protein is predominantly expressed in hematopoietic tissues and contains an extracellular region with only two N-linked glycosylation sites, a 20-residue transmembrane region and a highly positively charged 30-residue cytoplasmic tail, suggesting a role for SLAMF9 as an adhesion molecule. SLAMF9 is thought to function in the immune response as a coreceptor for lymphocyte activation.Synonyms: CD2 family member 10, CD2F-10, CD2F10, CD84 homolog 1, CD84-H1, SLAM family member 9