Klotho 抗体 (Center)
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- 抗原 See all Klotho (KL) 抗体
- Klotho (KL)
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抗原表位
- Center
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Klotho antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
- 特异性
- This antibody detects Klotho at center.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 16 amino acid peptide near the center of human KLOTHO
- Top Product
- Discover our top product KL Primary Antibody
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anti-Klotho (KL) (AA 516-955) antibody
KL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 401-500) antibodyKL 适用: 人, 小鼠, 大鼠 IHC (p), IHC (fro), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 517-956) antibodyKL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 720-769) antibodyKL 适用: 人, 大鼠, 兔, Cow, 犬, Pig, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 251-300) antibodyKL 适用: 人, 小鼠, 大鼠, 兔, 马, 犬, 豚鼠, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 986-1012), (C-Term) antibodyKL 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB21226 unconjugated
anti-Klotho (KL) (Middle Region) antibodyKL 适用: 人, 小鼠, 大鼠, 兔, 马, Cow, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (N-Term) antibodyKL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (Middle Region) antibodyKL 适用: 人, 小鼠, 大鼠, 兔, 马, Cow, 犬, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 765-981) antibodyKL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- Klotho (KL)
- 别名
- Klotho (KL 产品)
- 别名
- alpha-kl antibody, KL antibody, LOC100223456 antibody, klotho antibody, Klotho antibody, KL antibody, Kl antibody, kl antibody, LOC100533542 antibody
- 背景
- KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor. Three isoforms of KLOTHO are known to exist.Synonyms: EC 3.2.1.31, KL, Klotho
- 基因ID
- 9365
- NCBI登录号
- NP_004786
- UniProt
- Q9UEF7
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding
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