(5 references)-
- 抗原 See all CD163 抗体
- CD163
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD163 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody GHI/61 recognizes an extracellular epitope CD163, an approximately 130 kDa high affinity scavenger receptor expressed mainly on monocytes and macrophages, which binds hemoglobin-haptoglobin complex.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Hairy cell leukemia cells
- 克隆位点
- GHI-61
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD163 Primary Antibody
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anti-CD163 (CD163) (AA 1001-1121) antibody
CD163 适用: 人, 小鼠, 大鼠, Pig, 犬 WB, FACS, ELISA, IHC (p), IHC (fro), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD163 (CD163) (AA 1001-1121) antibody (FITC)CD163 适用: 人, 小鼠, 大鼠, Pig, 犬 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
anti-CD163 (CD163) (AA 43-196) antibodyCD163 适用: 人 IHC, ELISA, ISt, Coat, StM 宿主: 小鼠 Monoclonal M130-2162 unconjugated
anti-CD163 (CD163) (AA 43-196) antibodyCD163 适用: 人 WB, IHC, ISt, StM 宿主: 小鼠 Monoclonal M130-1210 unconjugated
anti-CD163 (CD163) (AA 42-259) antibodyCD163 适用: 人 WB, FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 7G5E2 unconjugated
anti-CD163 (CD163) (AA 697-972) antibodyCD163 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD163 (CD163) antibodyCD163 适用: 人 WB, FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal GHI-61 unconjugated
anti-CD163 (CD163) (AA 42-259) antibodyCD163 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 8B7D11 unconjugated
anti-CD163 (CD163) (AA 1092-1109), (C-Term) antibodyCD163 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD163 (CD163) (AA 47-201) antibodyCD163 适用: 人, 小鼠, 大鼠 WB, FACS, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 溶解方式
- No reconstitution is necessary.
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Do not freeze.
Avoid prolonged exposure to light. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Levels of soluble CD163 and severity of malaria in children in Ghana." in: Clinical and vaccine immunology : CVI, Vol. 15, Issue 9, pp. 1456-60, (2008) (PubMed).
: "Monocyte CD163 and CD36 expression in human whole blood and isolated mononuclear cell samples: influence of different anticoagulants." in: Clinical and vaccine immunology : CVI, Vol. 13, Issue 6, pp. 704-7, (2006) (PubMed).
: "CD163 identifies perivascular macrophages in normal and viral encephalitic brains and potential precursors to perivascular macrophages in blood." in: The American journal of pathology, Vol. 168, Issue 3, pp. 822-34, (2006) (PubMed).
: "A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily." in: European journal of immunology, Vol. 23, Issue 9, pp. 2320-5, (1993) (PubMed).
: "A monocyte/macrophage antigen recognized by the four antibodies GHI/61, Ber-MAC3, Ki-M8 and SM4." in: Immunology, Vol. 75, Issue 4, pp. 588-95, (1992) (PubMed).
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: "Levels of soluble CD163 and severity of malaria in children in Ghana." in: Clinical and vaccine immunology : CVI, Vol. 15, Issue 9, pp. 1456-60, (2008) (PubMed).
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- 抗原
- CD163
- 别名
- CD163 (CD163 产品)
- 别名
- DMBT1 antibody, CD163 antibody, CD163v2 antibody, CD163v3 antibody, M130 antibody, MM130 antibody, deleted in malignant brain tumors 1 protein-like antibody, CD163 molecule antibody, CD163 antigen antibody, LOC426820 antibody, CD163 antibody, Cd163 antibody
- 背景
- CD163 Molecule,CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.,MM130, SCARI1
- 基因ID
- 9332
- UniProt
- Q86VB7
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