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CD83 抗体

CD83 适用: 人, Non-Human Primate FACS, IHC (fro) 宿主: 小鼠 Monoclonal HB15e unconjugated
产品编号 ABIN775709
发货至: 中国
  • 抗原 See all CD83 抗体
    CD83
    适用
    • 71
    • 48
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    人, Non-Human Primate
    宿主
    • 60
    • 20
    • 10
    • 1
    小鼠
    克隆类型
    • 62
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    • 1
    单克隆
    标记
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    This CD83 antibody is un-conjugated
    应用范围
    • 56
    • 41
    • 18
    • 11
    • 10
    • 5
    • 3
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    • 1
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    The mouse monoclonal antibody HB15e recognizes an extracellular epitope of CD83, a 40-45 kDa type I glycoprotein expressed on mature dendritic cells.
    交叉反应 (详细)
    Human, Non-Human Primates
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human CD83-transfected Cos cells
    克隆位点
    HB15e
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD83 Primary Antibody
  • 应用备注
    Flow cytometry:Recommended dilution: 1-4 μg/mL, Positive control: peripheral blood-derived dendritic cells.
    Immunohistochemistry (frozen sections): acetone fixation.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    CD83
    别名
    CD83 (CD83 产品)
    别名
    BL11 antibody, HB15 antibody, CD83 molecule antibody, CD83 antigen antibody, Cd83 antibody, CD83 antibody
    背景
    CD83 Molecule,CD83 is a 40-45 kDa heavily glycosylated type I cell surface glycoprotein of immunoglobulin family. It is expressed on the surface of mature dendritic cells, Langerhans cells in the skin, and interdigitating reticulum cells in the lymphoid tissues. Low expression of CD83 has been reported in activated T and B cells. Cytoplasmic expression of CD83 can be detected also in monocytes and macrophages. CD83 is involved in modulation of antigen presentation. Soluble CD83 has immunoregulatory functions, it is able to down-regulate dendritic cell maturation and stimulation of T cells. In the developing immune system, release of soluble CD83 from dendritic cells upon stimulation by gram-positive or gram-negative bacteria has anti-allergic effect. Herpes simplex virus, on the other hand, causes CD83 degradation in mature dendritic cells.,BL11, HB15
    基因ID
    9308
    UniProt
    Q01151
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