TP53INP1 抗体 (AA 81-180)
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- 抗原 See all TP53INP1 抗体
- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
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抗原表位
- AA 81-180
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TP53INP1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human p53 DINP1
- 亚型
- IgG
- Top Product
- Discover our top product TP53INP1 Primary Antibody
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anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 138-205) antibody
TP53INP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (Internal Region) antibodyTP53INP1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 36-64), (N-Term) antibodyTP53INP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB29674 unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 181-210), (C-Term) antibodyTP53INP1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29563 unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (N-Term) antibodyTP53INP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (C-Term) antibodyTP53INP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 1-100) antibodyTP53INP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 43-72), (N-Term) antibodyTP53INP1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 188-218), (C-Term) antibodyTP53INP1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
- 别名
- P53 Dinp1 (TP53INP1 产品)
- 别名
- cb1036 antibody, wu:fb70a09 antibody, wu:fi13h08 antibody, zgc:158431 antibody, TP53INP1 antibody, 2700057G22Rik antibody, SIP antibody, SIP18 antibody, SIP27 antibody, Stinp antibody, Teap antibody, TP53DINP1 antibody, TP53INP1A antibody, TP53INP1B antibody, p53DINP1 antibody, Trp53inp1 antibody, tumor protein p53 inducible nuclear protein 1 antibody, tumor protein p53 inducible nuclear protein 1 S homeolog antibody, transformation related protein 53 inducible nuclear protein 1 antibody, TP53INP1 antibody, tp53inp1.S antibody, tp53inp1 antibody, Trp53inp1 antibody, Tp53inp1 antibody
- 背景
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Synonyms: Tumor protein p53-inducible nuclear protein 1, TP53INP1, P53DINP1, SIP
Background: Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.
- 基因ID
- 94241
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