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CPEB1 抗体 (AA 451-550) (Biotin)

CPEB1 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN761503
发货至: 中国
  • 抗原 See all CPEB1 抗体
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    抗原表位
    • 14
    • 10
    • 9
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-550
    适用
    • 48
    • 4
    • 4
    宿主
    • 45
    • 2
    • 1
    克隆类型
    • 48
    多克隆
    标记
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CPEB1 antibody is conjugated to Biotin
    应用范围
    • 43
    • 24
    • 13
    • 13
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CPEB1
    亚型
    IgG
    Top Product
    Discover our top product CPEB1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    别名
    CPEB1 (CPEB1 产品)
    别名
    CEBP antibody, CPE-BP1 antibody, CPEB antibody, AU024112 antibody, Cpeb antibody, mCPEB antibody, CPEB1 antibody, cpeb1 antibody, ZOR-1 antibody, cepb1b antibody, fd15c06 antibody, wu:fd15c06 antibody, zorba antibody, cytoplasmic polyadenylation element binding protein 1 antibody, hypothetical protein antibody, cytoplasmic polyadenylation element binding protein 1 L homeolog antibody, cytoplasmic polyadenylation element binding protein 1b antibody, cytoplasmic polyadenylation element binding protein 1 S homeolog antibody, CPEB1 antibody, Cpeb1 antibody, cpeb1 antibody, LOAG_17395 antibody, cpeb1.L antibody, cpeb1b antibody, cpeb1.S antibody
    背景

    Synonyms: CPE-binding protein 1, CPE-BP1, CPEB 1, CPEB, CPEB1, CPEB1 protein, CPEB1_HUMAN, Cytoplasmic polyadenylation binding protein 1, Cytoplasmic polyadenylation element binding protein, Cytoplasmic polyadenylation element binding protein 1, Cytoplasmic polyadenylation element-binding protein 1, h-CEBP, hCPEB-1

    Background: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.

    基因ID
    64506
    途径
    Synaptic Membrane
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