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ASAH2 抗体 (AA 701-780)

ASAH2 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN761276
发货至: 中国
  • 抗原 See all ASAH2 抗体
    ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
    抗原表位
    • 9
    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    AA 701-780
    适用
    • 32
    • 14
    • 5
    宿主
    • 33
    • 1
    克隆类型
    • 34
    多克隆
    标记
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASAH2 antibody is un-conjugated
    应用范围
    • 20
    • 20
    • 5
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ASAH2
    亚型
    IgG
    Top Product
    Discover our top product ASAH2 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
    别名
    ASAH2 (ASAH2 产品)
    别名
    BCDase antibody, HNAC1 antibody, LCDase antibody, N-CDase antibody, NCDase antibody, AI585898 antibody, N-acylsphingosine amidohydrolase 2 antibody, ASAH2 antibody, Asah2 antibody
    背景

    Synonyms: Acylsphingosine deacylase 2, ASAH2, ASAH2_HUMAN, BCDase, hCD, HNAC1, LCDase, MGC129777, mitochondrial ceramidase, N acylsphingosine amidohydrolase non lysosomal ceramidase 2, N acylsphingosine amidohydrolase 2, N CDase, N-acylsphingosine amidohydrolase 2, N-CDase, NCDase, Neutral ceramidase soluble form, Non lysosomal ceramidase, Non-lysosomal ceramidase.

    Background: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

    基因ID
    2298
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