ASAH2 抗体 (AA 701-780)
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- 抗原 See all ASAH2 抗体
- ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
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抗原表位
- AA 701-780
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASAH2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ASAH2
- 亚型
- IgG
- Top Product
- Discover our top product ASAH2 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
- 别名
- ASAH2 (ASAH2 产品)
- 别名
- BCDase antibody, HNAC1 antibody, LCDase antibody, N-CDase antibody, NCDase antibody, AI585898 antibody, N-acylsphingosine amidohydrolase 2 antibody, ASAH2 antibody, Asah2 antibody
- 背景
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Synonyms: Acylsphingosine deacylase 2, ASAH2, ASAH2_HUMAN, BCDase, hCD, HNAC1, LCDase, MGC129777, mitochondrial ceramidase, N acylsphingosine amidohydrolase non lysosomal ceramidase 2, N acylsphingosine amidohydrolase 2, N CDase, N-acylsphingosine amidohydrolase 2, N-CDase, NCDase, Neutral ceramidase soluble form, Non lysosomal ceramidase, Non-lysosomal ceramidase.
Background: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
- 基因ID
- 2298
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