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DAB2 抗体 (AA 31-130)

DAB2 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN760961
发货至: 中国
  • 抗原 See all DAB2 抗体
    DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
    抗原表位
    • 15
    • 15
    • 13
    • 13
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 31-130
    适用
    • 51
    • 32
    • 18
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 67
    • 11
    • 1
    克隆类型
    • 70
    • 9
    多克隆
    标记
    • 17
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DAB2 antibody is un-conjugated
    应用范围
    • 66
    • 31
    • 25
    • 25
    • 16
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DAB2
    亚型
    IgG
    Top Product
    Discover our top product DAB2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
    别名
    Dab2 (DAB2 产品)
    别名
    DOC-2 antibody, DOC2 antibody, 5730435J12Rik antibody, AA960054 antibody, AI957090 antibody, D15Wsu122e antibody, D630005B22Rik antibody, Doc-2 antibody, Doc2 antibody, p96 antibody, DAB2, clathrin adaptor protein antibody, disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) antibody, Dab, mitogen-responsive phosphoprotein, homolog 2 antibody, disabled 2, mitogen-responsive phosphoprotein antibody, DAB2 antibody, dab2 antibody, Dab2 antibody
    背景

    Synonyms: DOC2, DOC-2, Disabled homolog 2, Differentially-expressed protein 2, DAB2

    Background: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

    基因ID
    1601
    UniProt
    P98082
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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