CTCFL 抗体 (AA 351-450)
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- 抗原 See all CTCFL 抗体
- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
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抗原表位
- AA 351-450
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CTCFL antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BORIS/CT27
- 亚型
- IgG
- Top Product
- Discover our top product CTCFL Primary Antibody
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anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-270) antibody
CTCFL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (N-Term) antibodyCTCFL 适用: 人 WB, ChIP-seq, ChIP 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 9-26) antibodyCTCFL 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 617-650) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal RB54304 unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-636) antibodyCTCFL 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) antibodyCTCFL 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 211-260) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 36-85) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-270) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) antibodyCTCFL 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
- 别名
- Ct27 (CTCFL 产品)
- 别名
- BORIS antibody, CT27 antibody, CTCF-T antibody, HMGB1L1 antibody, dJ579F20.2 antibody, CTCFL antibody, Boris antibody, OTTMUSG00000016680 antibody, CCCTC-binding factor like antibody, CCCTC-binding factor (zinc finger protein)-like antibody, CTCFL antibody, Ctcfl antibody
- 背景
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Synonyms: BORIS like protein, Brother of the regulator of imprinted sites, Cancer/testis antigen 27, CCCTC binding factor zinc finger protein like, CCCTC-binding factor, CT27, CTCF paralog, CTCF T, CTCF-like protein, CTCFL, CTCFL_HUMAN, HMG 1L1, HMGB1L1, Putative high mobility group protein 1 like 1, Putative high mobility group protein B1 like 1, Transcriptional repressor CTCFL, Zinc finger protein CTCF-T.
Background: Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
- 基因ID
- 140690
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