POMT1 抗体 (AA 651-747)
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- 抗原 See all POMT1 抗体
- POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
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抗原表位
- AA 651-747
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POMT1 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human POMT1
- 亚型
- IgG
- Top Product
- Discover our top product POMT1 Primary Antibody
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anti-Protein-O-Mannosyltransferase 1 (POMT1) (AA 318-513) antibody
POMT1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein-O-Mannosyltransferase 1 (POMT1) (AA 706-735), (C-Term) antibodyPOMT1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB31305 unconjugated
anti-Protein-O-Mannosyltransferase 1 (POMT1) (AA 706-735), (C-Term) antibodyPOMT1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein-O-Mannosyltransferase 1 (POMT1) (AA 713-743), (C-Term) antibodyPOMT1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Protein-O-Mannosyltransferase 1 (POMT1) (AA 648-697) antibodyPOMT1 适用: 人, 小鼠, Pig, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Protein-O-Mannosyltransferase 1 (POMT1) (AA 310-550) antibodyPOMT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein-O-Mannosyltransferase 1 (POMT1) (AA 318-513) antibodyPOMT1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
- 别名
- Pomt1 (POMT1 产品)
- 别名
- LGMD2K antibody, MDDGA1 antibody, MDDGB1 antibody, MDDGC1 antibody, RT antibody, AI505244 antibody, protein O-mannosyltransferase 1 antibody, protein-O-mannosyltransferase 1 antibody, POMT1 antibody, Pomt1 antibody
- 背景
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Synonyms: POMT1_HUMAN, Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1.
Background: POMT1 (Protein O mannosyl transferase 1) is a multipass membrane protein that is found in the endoplasmic reticulum. POMT1 catalyses the transfer of mannosyl residues to the hydroxyl groups of serine or threonine residues. Enzymatic activity is dependent on co expression of POMT1 with POMT2. Defects in the POMT1 gene are associated with Walker-Warburg syndrome (WWS), a congential muscular dystrophy that is associated with mental retardation and is usually lethal within the first few months of life. Other defects in the POMT1 gene result in limb girdle muscular dystrophy type 2K (LGMD2K), which is associated with mild mental retardation. Studies in Drosophila suggest that mutation of POMT1 alters the efficacy of synaptic transmission and a change in subunit composition of post synaptic glutamate receptors at the neuromuscular junction. Missense mutations in POMT1 have been associated with glioneuronal and glial brain tumours.
- 基因ID
- 10585
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