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MMP28 抗体 (AA 201-300)

MMP28 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN759191
发货至: 中国
  • 抗原 See all MMP28 抗体
    MMP28 (Matrix Metallopeptidase 28 (MMP28))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    适用
    • 46
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    宿主
    • 42
    • 4
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 20
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP28 antibody is un-conjugated
    应用范围
    • 29
    • 21
    • 18
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Pig,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MMP28
    亚型
    IgG
    Top Product
    Discover our top product MMP28 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MMP28 (Matrix Metallopeptidase 28 (MMP28))
    别名
    MMP-28 (MMP28 产品)
    别名
    mmp28b antibody, XMMP-28 antibody, MGC68506 antibody, MMP28 antibody, EPILYSIN antibody, MM28 antibody, MMP-28 antibody, MMP25 antibody, D130023P12 antibody, matrix metallopeptidase 28 S homeolog antibody, matrix metallopeptidase 28 antibody, matrix metallopeptidase 28 (epilysin) antibody, mmp28.S antibody, MMP28 antibody, Mmp28 antibody
    背景

    Synonyms: Epilysin, Matrix Metalloproteinase 28, MM 28, MM28, MMP 28, MMP-28, MMP28.

    Background: Matrix Metalloproteinase 28, also known as epilysin, was first cloned from human skin keratinocytes and described to reflect its role in the remodeling of the epidermis. It was found in testis, as well as heart, brain, placenta, lung, prostate, intestine, and colon. MMP28 was later cloned from human lung and found in lung, kidney, brain, skeletal muscle, and several tumor cell lines. At least three MMP28 transcripts of 2.6, 2.0, and 1.2 kb have been reported possibly representing alternatively spliced forms of MMP28. There are two human sequences (isoform1 and isoform 2) which encode proteins of 520 and 393 amino acids with predicted masses of 58.9 and 44.5 kDa respectively. The mouse sequence contains two inserts of 41 and 39 amino acids respectively, relative to the human sequence. Mouse epilysin has a predicted molecular mass of approx. 70 kDa. Mouse and human epilysin are highly conserved and share 97 % identical residues. Epilysin (MMP-28) contains the key domains of the other MMPs: a signal peptide, conserved cysteine-containing prodomain (with a furin cleavage site), conserved histidine-containing catalytic domain, hinge domain, and hemopexin domain. MMP28 has a furin cleavage site, similar to MMP11, and is cleaved by the prohormone convertase family of enzymes. Sequence identity between MMP28 and the other MMPs is low overall. MMP28 is most closely related to MMP19 (39 % sequence identity). Recombinant MMP28 degrades casein.

    基因ID
    79148
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