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PCDHGB5 抗体 (AA 21-120) (Biotin)

PCDHGB5 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN758473
发货至: 中国
  • 抗原 See all PCDHGB5 抗体
    PCDHGB5 (Protocadherin gamma Subfamily B, 5 (PCDHGB5))
    抗原表位
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    适用
    • 30
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 29
    • 1
    克隆类型
    • 30
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCDHGB5 antibody is conjugated to Biotin
    应用范围
    • 24
    • 13
    • 13
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PCDHGB5
    亚型
    IgG
    Top Product
    Discover our top product PCDHGB5 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    PCDHGB5 (Protocadherin gamma Subfamily B, 5 (PCDHGB5))
    别名
    PCDHGB5 (PCDHGB5 产品)
    别名
    PCDH-GAMMA-B5 antibody, protocadherin gamma subfamily B, 5 antibody, PCDHGB5 antibody, Pcdhgb5 antibody
    背景

    Synonyms: PCDH gamma B5, PCDHGB 5, Protocadherin gamma B5, Protocadherin gamma subfamily B 5, PCDGH_HUMAN.

    Background: PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

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