SNRPE 抗体 (pSer446)
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- 抗原 See all SNRPE 抗体
- SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
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抗原表位
- pSer446
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNRPE antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human B-Raf around the phosphorylation site of Ser446
- 亚型
- IgG
- Top Product
- Discover our top product SNRPE Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
- 别名
- B-Raf (SNRPE 产品)
- 别名
- B-raf antibody, HYPT11 antibody, SME antibody, Sm-E antibody, b-raf antibody, sm-e antibody, sme antibody, SmE antibody, snRNP-E antibody, AL022645 antibody, C76690 antibody, zgc:56682 antibody, small nuclear ribonucleoprotein polypeptide E antibody, small nuclear ribonucleoprotein polypeptide E L homeolog antibody, small nuclear ribonucleoprotein E antibody, SNRPE antibody, snrpe.L antibody, Snrpe antibody, snrpe antibody
- 背景
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Synonyms: B Raf phospho S446, p-B Raf phospho S446, 94 kDa B raf protein, B raf 1, B Raf proto oncogene serine threonine protein kinase, BRAF 1, Braf, BRAF1, cRmil, MGC126806, MGC138284, Murine sarcoma viral v-raf oncogene homolog B1, Murine sarcoma viral v raf oncogene homolog B1, p94, RAFB 1, RAFB1, v raf murine sarcoma viral oncogene homolog B1, FLJ95109.
Background: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.
- 基因ID
- 673
- 途径
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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