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NCEH1 抗体 (AA 151-250)

NCEH1 适用: 人 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN755752
发货至: 中国
  • 抗原 See all NCEH1 抗体
    NCEH1 (Neutral Cholesterol Ester Hydrolase 1 (NCEH1))
    抗原表位
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    适用
    • 21
    • 13
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 20
    • 1
    克隆类型
    • 21
    多克隆
    标记
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NCEH1 antibody is un-conjugated
    应用范围
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Human,Mouse,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human AADACL1
    亚型
    IgG
    Top Product
    Discover our top product NCEH1 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    NCEH1 (Neutral Cholesterol Ester Hydrolase 1 (NCEH1))
    别名
    AADACL1 (NCEH1 产品)
    别名
    AADACL1 antibody, NCEH antibody, Aadacl1 antibody, B230106I24Rik antibody, CPO-BP antibody, Nceh antibody, RGD1311104 antibody, nceh antibody, aadacl1 antibody, MGC79479 antibody, nceh1b antibody, zgc:153038 antibody, zgc:92416 antibody, neutral cholesterol ester hydrolase 1 antibody, neutral cholesterol ester hydrolase 1 S homeolog antibody, neutral cholesterol ester hydrolase 1b, tandem duplicate 1 antibody, neutral cholesterol ester hydrolase 1a antibody, NCEH1 antibody, Nceh1 antibody, nceh1 antibody, nceh1.S antibody, nceh1b.1 antibody, nceh1a antibody
    背景

    Synonyms: Arylacetamide deacetylase like 1, Arylacetamide deacetylase-like 1, Kiaa1363, NCEH, Nceh1, NCEH1_HUMAN, Neutral cholesterol ester hydrolase 1, Neutral cholesterol ester hydrolase.

    Background: The assembly of very-low-density lipoproteins (VLDLs) in the secretory apparatus of the hepatocyte relies on the mobilization of triacylglycerol (TAG) from the cytosolic pool by lipolysis and re-esterification. However, some of the re-esterified TAG products are returned to the cytosolic pool in the liver, which protects vulnerable body tissues from excess lipotoxic non-esterified fatty acids in the plasma. Some of the lipases involved in this process include arylacetamide deacetylase (AADAC) and its related proteins AADACL1 and AADACL2. AADAC, a single pass type II membrane protein of the endoplasmic reticulum, is expressed in hepatocytes, intestinal mucosal cells, pancreas and adrenal gland. It plays an important role in the metabolic activation of arylamine substrates to ultimate carcinogens. AADACL1 hydrolyzes the metabolic intermediate 2-acetyl monoalkylglycerol, and its inactivation results in disruption of ether lipid metabolism in cancer cells and impaired cell migration and tumor growth.

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