Phospholamban 抗体 (AA 1-35)
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- 抗原 See all Phospholamban (PLN) 抗体
- Phospholamban (PLN)
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抗原表位
- AA 1-35
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Phospholamban antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human phospholamban
- 亚型
- IgG
- Top Product
- Discover our top product PLN Primary Antibody
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anti-Phospholamban (PLN) (AA 1-52) antibody
PLN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-30) antibodyPLN 适用: 人 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (pSer16) antibodyPLN 适用: 人 ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (N-Term) antibodyVerified PLN 适用: 人, 大鼠 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Phospholamban (PLN) (Thr17) antibodyPLN 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-52) antibodyPLN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) antibodyPLN 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-30) antibodyPLN 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phospholamban (PLN) (pThr17) antibodyPLN 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (pSer16), (pThr17) antibodyPLN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Phospholamban (PLN)
- 别名
- phospholamban (PLN 产品)
- 别名
- LOC100226261 antibody, plb antibody, cmd1p antibody, CMD1P antibody, CMH18 antibody, PLB antibody, Plb antibody, Plm antibody, phospholamban antibody, PLN antibody, pln antibody, Pln antibody
- 背景
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Synonyms: Cardiac phospholamban, CMD1P, PLB, PLN, PPLA_HUMAN.
Background: The Sarco(endo)plasmic-reticulum (SER) regulatory protein, Phospholamban (PLB), is a small, plasma membrane-associated protein found in the SER of cardiac, smooth and slow-twitch muscle. Believed to assemble into a pentamer, PLB regulates cardiac contractility and Ca2+ affinity for cardiac SER Ca2+ ATPase (SERCA2a). Non-phosphorylated PLB associates with SERCA2a, and inhibits Ca2+ reuptake into the SER. PLB activation occurs when key Serine/Threonine residues in PLB (Ser-10, Ser-16, Thr-17) are phosphorylated by numerous effectors, which include PKC, PKA, PKG, and CaM kinase. Phosphorylation of PLB causes dissociation from SERCA2a and a subsequent increase in the rate of Ca2+ reuptake into the SER, which accelerates ventricular relaxation.
- 基因ID
- 5350
- 途径
- Negative Regulation of Transporter Activity
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