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RRM2B 抗体 (AA 131-230) (Biotin)

RRM2B 适用: 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN755025
发货至: 中国
  • 抗原 See all RRM2B 抗体
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    抗原表位
    • 14
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 131-230
    适用
    • 37
    • 33
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 48
    • 3
    克隆类型
    • 48
    • 3
    多克隆
    标记
    • 20
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRM2B antibody is conjugated to Biotin
    应用范围
    • 44
    • 22
    • 13
    • 13
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Cow,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human p53R2/RRM2B
    亚型
    IgG
    Top Product
    Discover our top product RRM2B Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    别名
    p53R2 (RRM2B 产品)
    别名
    p53r2 antibody, RRM2B antibody, MTDPS8A antibody, MTDPS8B antibody, P53R2 antibody, p53R2 antibody, ribonucleotide reductase M2 B (TP53 inducible) S homeolog antibody, ribonucleotide reductase regulatory TP53 inducible subunit M2B antibody, ribonucleotide reductase M2 B (TP53 inducible) antibody, rrm2b.S antibody, RRM2B antibody, rrm2b antibody, Rrm2b antibody
    背景

    Synonyms: DKFZp686M05248, MGC102856, MGC42116, MTDPS8A, MTDPS8B, p53 inducible ribonucleotide reductase small subunit 2 homolog, p53 inducible ribonucleotide reductase small subunit 2 like protein, p53 R2, p53-inducible ribonucleotide reductase small subunit 2-like protein, p53R2, Ribonucleoside diphosphate reductase M2 subunit B, Ribonucleoside-diphosphate reductase subunit M2 B, Ribonucleotide reductase M2 B TP53 inducible, Ribonucleotide reductase M2 B, Ribonucleotide reductase small subunit like 2 p53 inducible, RIR2B_HUMAN, RRM 2B, RRM2B, TP53 inducible ribonucleotide reductase M2 B, TP53-inducible ribonucleotide reductase M2 B.

    Background: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010].

    基因ID
    50484
    途径
    p53 Pathway, Negative Regulation of intrinsic apoptotic Signaling
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