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G6PC 抗体

G6PC 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN752998
发货至: 中国
  • 抗原 See all G6PC 抗体
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    适用
    • 42
    • 21
    • 20
    • 15
    • 13
    • 12
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, Pig
    宿主
    • 42
    • 1
    克隆类型
    • 42
    • 1
    多克隆
    标记
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This G6PC antibody is un-conjugated
    应用范围
    • 30
    • 19
    • 15
    • 11
    • 10
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    Cow, 犬, 人, 小鼠, Pig, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha
    亚型
    IgG
    Top Product
    Discover our top product G6PC Primary Antibody
  • 应用备注
    WB(1:100-500)
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • Yao, Zhuang, Du, Cheng, Yang, Guan, Hu, Zhu, Christine, Shi, Hua: "Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2689-700, (2013) (PubMed).

  • 抗原
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    别名
    Glucose 6 phosphatase alpha (G6PC 产品)
    别名
    AW107337 antibody, G6Pase antibody, G6pt antibody, Glc-6-Pase antibody, G6PC1 antibody, G6PT antibody, GSD1 antibody, GSD1a antibody, G-6-Pase antibody, glucose-6-phosphatase, catalytic antibody, glucose-6-phosphatase catalytic subunit antibody, glucose-6-phosphatase, catalytic subunit antibody, G6pc antibody, G6PC antibody
    背景

    Synonyms: glucose-6-phosphatase, catalytic subunit, GSD1, AW107337, G-6-Pase, G6Pase, G6Pase-alpha, g6pc, G6PC_HUMAN, G6PT, Glucose-6-phosphatase alpha, Glucose-6-phosphatase, GSD1a, MGC163350, MGC93613, RP23-281C18.19.

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-i±, a second form, designated G6Pase-i², contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-i², also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-i² hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-i² may play an integral role in diabetes and glycogen storage diseases (GSDs).

    分子量
    40kDa
    基因ID
    2538
    途径
    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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