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ATG5 抗体 (AA 101-200)

Name: ATG5 抗体 (AA 101-200)
SKU: ABIN752413
Availability: OutOfStock

ATG5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded mouse kidney labeled with Rabbit Anti-APG5L/ATG5 Polyclonal Antibody (ABIN752413) at 1:100 followed by conjugation to the secondary antibody and DAB staining. (ATG5 抗体 (AA 101-200))

IHC

Formalin-fixed and paraffin embedded rat brain tissue labeled with Rabbit Anti-APG5L/ATG5 Polyclonal Antibody (ABIN752413) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (ATG5 抗体 (AA 101-200))

IHC

Formalin-fixed and paraffin embedded mouse kidney labeled with Rabbit Anti-APG5L/ATG5 Polyclonal Antibody at 1:100 followed by conjugation to the secondary antibody and DAB staining. (ATG5 抗体 (AA 101-200))

IHC (p)

Formalin-fixed and paraffin embedded rat brain tissue labeled with Rabbit Anti-APG5L/ATG5 Polyclonal Antibody ) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (ATG5 抗体 (AA 101-200))

IHC (p)

IHC

Lane 1: rat heart lysates Lane 2: rat brain lysates probed with Anti APG5L/ATG5 Polyclonal Antibody, Unconjugated (ABIN752413) at 1:200 in 4 °C. (ATG5 抗体 (AA 101-200))

SDS

6 images

(6 references)

产品编号 ABIN752413

发货至: 中国

Datasheet as PDF

抗原 See all ATG5 抗体

ATG5 (ATG5 Autophagy Related 5 (ATG5))
抗原表位
15

12

7

6

6

5

5

4

4

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1
AA 101-200
适用
108

47

39

6

6

5

5

4

4

4

4

3

3

2
人, 小鼠, 大鼠
宿主
83

22

4

1
兔
Compatible Secondaries
克隆类型
85

25
多克隆
标记
52

8

7

6

6

6

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This ATG5 antibody is un-conjugated
应用范围
72

53

33

16

14

14

13

12

10

7

4

3

3

2

2

2

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Cow,Pig,Horse,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human APG5L

亚型

IgG
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-275) antibody
ATG5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG5 Autophagy Related 5 (ATG5) (AA 209-238), (C-Term) antibody
ATG5 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7547 unconjugated

anti-ATG5 Autophagy Related 5 (ATG5) (AA 144-275) antibody
ATG5 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3C7A8 unconjugated

anti-ATG5 Autophagy Related 5 (ATG5) (AA 176-275) antibody
ATG5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated

anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-119) antibody
ATG5 适用: 人 WB, ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal ATG5-2101 unconjugated

anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-30) antibody
ATG5 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-30), (N-Term) antibody
ATG5 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-ATG5 Autophagy Related 5 (ATG5) (C-Term) antibody
ATG5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-ATG5 Autophagy Related 5 (ATG5) (AA 28-275) antibody
ATG5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-ATG5 Autophagy Related 5 (ATG5) antibody
KO Validated ATG5 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Li, Li, Wang, Xie, Zhou, Meng, Ding, Ge, Chen: "Autophagy contributes to 4-Amino-2-Trifluoromethyl-Phenyl Retinate-induced differentiation in human acute promyelocytic leukemia NB4 cells." in: Toxicology and applied pharmacology, Vol. 319, pp. 1-11, (2017) (PubMed).

Lang, Qin, Li, Zhang, Fang, Hao: "Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells." in: PLoS ONE, Vol. 10, Issue 6, pp. e0129196, (2015) (PubMed).

Zhang, Ma, Qi, Wei, Zhang, Li, Chiu: "P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis." in: Oncotarget, Vol. 6, Issue 2, pp. 789-801, (2015) (PubMed).

Tang, Li, Wei, Zhang, Chiu, Hasenmayer, Zhang, Zhang: "Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal squamous cell carcinoma." in: Cancer letters, Vol. 336, Issue 2, pp. 325-37, (2013) (PubMed).

Song, Kou, Zou, Gao, Zeng, Xie: "Involvement of autophagy in tri-ortho-cresyl phosphate- induced delayed neuropathy in hens." in: Neurochemistry international, Vol. 64, pp. 1-8, (2013) (PubMed).
抗原

ATG5 (ATG5 Autophagy Related 5 (ATG5))

别名

APG5L (ATG5 产品)

别名

APG5 antibody, APG5-LIKE antibody, APG5L antibody, ASP antibody, hAPG5 antibody, ATG5 antibody, CG1643 antibody, DmAtg5 antibody, Dmel\\CG1643 antibody, atg5 antibody, 2010107M05Rik antibody, 3110067M24Rik antibody, AW319544 antibody, Apg5l antibody, Atg5l antibody, C88337 antibody, Paddy antibody, apg5l antibody, zgc:100934 antibody, ATATG5 antibody, AUTOPHAGY 5 antibody, MKP11.20 antibody, MKP11_20 antibody, autophagy related 5 antibody, Autophagy-related 5 antibody, ATG5 autophagy related 5 homolog (S. cerevisiae) antibody, autophagy related 5 L homeolog antibody, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 antibody, autophagy protein Apg5 family antibody, ATG5 antibody, Atg5 antibody, atg5 antibody, atg5.L antibody, APG5 antibody

背景

Synonyms: ASP, APG5, APG5L, hAPG5, APG5-LIKE, Autophagy protein 5, Apoptosis-specific protein, ATG5
Background: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. The ATG12-ATG5 conjugate also negatively regulates the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Also plays a role in translation or delivery of incoming viral RNA to the translation apparatus. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT2 via the autophagic pathway. May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.

基因ID

9474

UniProt

Q9H1Y0

途径

Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy