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TXNIP 抗体 (AA 101-200)

Name: TXNIP 抗体 (AA 101-200)
SKU: ABIN750808
Availability: OutOfStock

TXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-TXNIP Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (TXNIP 抗体 (AA 101-200))

IHC (p)

1 image

(2 references)

产品编号 ABIN750808

发货至: 中国

Datasheet as PDF

抗原 See all TXNIP 抗体

TXNIP (Thioredoxin Interacting Protein (TXNIP))
抗原表位
15

14

9

8

5

5

3

1

1

1

1

1

1

1

1

1

1
AA 101-200
适用
67

47

32

5

4

4

3

3

2

2

1

1
人, 小鼠, 大鼠
宿主
76

5
兔
Compatible Secondaries
克隆类型
68

13
多克隆
标记
30

8

7

6

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This TXNIP antibody is un-conjugated
应用范围
57

31

14

13

13

8

7

5

4

3

2

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Pig,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human TXNIP

亚型

IgG

Top Product

Discover our top product TXNIP Primary Antibody
anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-166) antibody
TXNIP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibody
TXNIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibody
TXNIP 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibody
TXNIP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30652 unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-30), (N-Term) antibody
TXNIP 适用: 人 WB 宿主: 兔 Polyclonal RB41554 unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibody
TXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibody
TXNIP 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 绵羊, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibody
TXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 121-170) antibody
TXNIP 适用: 人, 犬, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Liu, Sun, Wang, Zhang, Zhao, Zhao: "Silymarin attenuated paraquat-induced cytotoxicity in macrophage by regulating Trx/TXNIP complex, inhibiting NLRP3 inflammasome activation and apoptosis." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 46, pp. 265-272, (2017) (PubMed).

Li, Shen, Sun, Li, Sun, Liu, Zhang, Huang, Meng, Li: "MicroRNA-20a negatively regulates expression of NLRP3-inflammasome by targeting TXNIP in adjuvant-induced arthritis fibroblast-like synoviocytes." in: Joint, bone, spine : revue du rhumatisme, Vol. 83, Issue 6, pp. 695-700, (2016) (PubMed).
抗原

TXNIP (Thioredoxin Interacting Protein (TXNIP))

别名

TXNIP (TXNIP 产品)

别名

EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody

背景

Synonyms: THIF, VDUP1, HHCPA78, EST01027, Thioredoxin-interacting protein, Thioredoxin-binding protein 2, Vitamin D3 up-regulated protein 1, TXNIP
Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).

基因ID

10628

UniProt

Q9H3M7

途径

Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome