Cyclic GMP 抗体
cGMP
IF (cc), IF (p), ELISA, IHC (fro), IHC (p)
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all Cyclic GMP (cGMP) 抗体
- Cyclic GMP (cGMP)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cyclic GMP antibody is un-conjugated
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Due to the fact that BSA is used as the carrier, this antibody will cross-react with Albumin.
- 交叉反应
- 大鼠
- 交叉反应 （详细）
- cGMP
- 纯化方法
- Purified by Protein A.
- 免疫原
- OVA conjugated cGMP
- 亚型
- IgG
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- 应用备注
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IHC-P 1:100-500
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Cyclic GMP (cGMP)
- 别名
- Cgmp (cGMP 产品)
- 物质类
- Chemical
- 背景
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Synonyms: Cyclic GMP, Cyclic guanosine monophosphate, Guanosine 3 5 Cyclic Monophosphate.
Background: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
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