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TLR6 抗体 (AA 301-400)

Name: TLR6 抗体 (AA 301-400)
SKU: ABIN749573
Availability: OutOfStock

TLR6 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded mouse stomach labeled with Anti-TLR6/CD286 Polyclonal Antibody, Unconjugated (ABIN749573) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (TLR6 抗体 (AA 301-400))

IHC

Rat splenocytes stained with Anti- TLR6/CD286 Polyclonal Antibody, PE-CY5. (TLR6 抗体 (AA 301-400))

FACS

Mouse thymus lysates probed with TLR6 Polyclonal Antibody, unconjugated at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 90 minutes at 37°C. (TLR6 抗体 (AA 301-400))

8 images

(1 reference)

产品编号 ABIN749573

发货至: 中国

Datasheet as PDF

抗原 See all TLR6 抗体

TLR6 (Toll-Like Receptor 6 (TLR6))
抗原表位
8

8

7

5

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 301-400
适用
61

20

3

3

1

1

1
人, 小鼠, 大鼠
宿主
45

18

1
兔
Compatible Secondaries
克隆类型
45

19
多克隆
标记
37

8

5

3

3

2

1

1

1

1

1

1
This TLR6 antibody is un-conjugated
应用范围
36

34

26

21

8

7

6

5

4

1

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

交叉反应

人, 小鼠, 大鼠

预测反应

Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human TLR6

亚型

IgG
anti-Toll-Like Receptor 6 (TLR6) (AA 393-423) antibody
TLR6 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 6 (TLR6) (AA 722-753) antibody
TLR6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 6 (TLR6) (AA 32-586) antibody
TLR6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 6 (TLR6) (AA 608-796) antibody
TLR6 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 6 (TLR6) (AA 408-424) antibody (PE)
TLR6 适用: 人 FACS 宿主: 小鼠 Monoclonal 86B1153-2 PE

anti-Toll-Like Receptor 6 (TLR6) (AA 32-200) antibody
TLR6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 6 (TLR6) (AA 722-753), (C-Term) antibody
TLR6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 6 (TLR6) (AA 1-30) antibody
TLR6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 6 (TLR6) (C-Term) antibody
TLR6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 6 (TLR6) (C-Term) antibody
TLR6 适用: 人, 小鼠 IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Shmuel-Galia, Aychek, Fink, Porat, Zarmi, Bernshtein, Brenner, Jung, Shai: "Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis." in: The EMBO journal, Vol. 35, Issue 6, pp. 685-98, (2016) (PubMed).
抗原

TLR6 (Toll-Like Receptor 6 (TLR6))

别名

TLR6 (TLR6 产品)

别名

TLR1 antibody, TLR16 antibody, CD286 antibody, TLR-6 antibody, toll-like receptor 1 family member A antibody, toll like receptor 6 antibody, toll-like receptor 6 antibody, TLR1A antibody, TLR6 antibody, Tlr6 antibody

背景

Synonyms: CD286, Toll-like receptor 6, TLR6
Background: Participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. In complex with TLR4, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

基因ID

10333

UniProt

Q9Y2C9

途径

TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades