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SIRPA 抗体 (AA 151-250)

Name: SIRPA 抗体 (AA 151-250)
SKU: ABIN749453
Availability: OutOfStock

SIRPA 适用: 人, 小鼠 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

Mouse spleen and bone lysates probed with Rabbit Anti-SIRP Alpha Polyclonal Antibody, Unconjugated at 1:500 for 90 min at 37˚C. (SIRPA 抗体 (AA 151-250))

Human U937 probed with SIRP Alpha Polyclonal Antibody at 1:100 for 30 minutes followed by incubation with a PE Conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). (SIRPA 抗体 (AA 151-250))

FACS

2 images

产品编号 ABIN749453

发货至: 中国

Datasheet as PDF

抗原 See all SIRPA 抗体

SIRPA (Signal-Regulatory Protein alpha (SIRPA))
抗原表位
15

14

5

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 151-250
适用
69

38

32

9

8

3

3

3
人, 小鼠
宿主
57

31

1

1
兔
Compatible Secondaries
克隆类型
56

34
多克隆
标记
45

10

7

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This SIRPA antibody is un-conjugated
应用范围
55

43

19

17

13

12

11

9

9

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA

交叉反应

人, 小鼠

预测反应

Rat,Dog,Cow,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CD172a

亚型

IgG

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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 235-373) antibody
SIRPA 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2H7E2 unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 395-504) antibody
SIRPA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 56-296) antibody
SIRPA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (C-Term) antibody
SIRPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) antibody
SIRPA 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 105-324) antibody
SIRPA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-373) antibody
SIRPA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 1-508) antibody
SIRPA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-370) antibody
SIRPA 适用: 人 FACS, ELISA, IP, IF 宿主: 兔 Monoclonal DM8 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

SIRPA (Signal-Regulatory Protein alpha (SIRPA))

别名

Sirp alpha (SIRPA 产品)

别名

BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody

背景

Synonyms: BIT, MFR, P84, SIRP, MYD-1, SHPS1, CD172A, PTPNS1, Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1, Signal-regulatory protein alpha-2, Sirp-alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-3, SIRPA, MYD1
Background: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.

基因ID

140885

UniProt

P78324