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NFAM1 抗体 (AA 81-180)

NFAM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN749033
发货至: 中国
  • 抗原 See all NFAM1 抗体
    NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))
    抗原表位
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 81-180
    适用
    • 34
    • 17
    • 17
    • 3
    人, 小鼠, 大鼠
    宿主
    • 31
    • 3
    克隆类型
    • 33
    • 1
    多克隆
    标记
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFAM1 antibody is un-conjugated
    应用范围
    • 23
    • 12
    • 12
    • 8
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NFAM1
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Sambandam, Sundaram, Saigusa, Balasubramanian, Reddy: "NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone." in: Bone, Vol. 101, pp. 236-244, (2018) (PubMed).

  • 抗原
    NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))
    别名
    NFAM1 (NFAM1 产品)
    别名
    4921501M20Rik antibody, Cnaip antibody, CNAIP antibody, bK126B4.4 antibody, RGD1308316 antibody, NFAT activating protein with ITAM motif 1 antibody, Nfat activating molecule with ITAM motif 1 antibody, NFAM1 antibody, Nfam1 antibody
    背景

    Synonyms: CNAIP, bK126B4.4, NFAT activation molecule 1, Calcineurin/NFAT-activating ITAM-containing protein, NFAT-activating protein with ITAM motif 1, NFAM1

    Background: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.

    基因ID
    150372
    UniProt
    Q8NET5
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