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- 抗原 See all LAG3 抗体
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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抗原表位
- AA 210-260
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LAG3 antibody is conjugated to PE
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
- 亚型
- IgG
- Top Product
- Discover our top product LAG3 Primary Antibody
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- 应用备注
- FCM(1:20-100)
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." in: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).
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CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." in: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).
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- 抗原
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- 别名
- Lymphocyte Activation Gene 3 (LAG3 产品)
- 别名
- CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody
- 背景
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Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3
Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
- 基因ID
- 297596
- UniProt
- Q5BK54
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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