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Integrin Alpha2b 抗体 (AA 351-450)

CD41 适用: 人, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN748358
发货至: 中国
  • 抗原 See all Integrin Alpha2b (CD41) 抗体
    Integrin Alpha2b (CD41)
    抗原表位
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    适用
    • 113
    • 30
    • 20
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 70
    • 45
    • 21
    克隆类型
    • 87
    • 43
    • 1
    多克隆
    标记
    • 54
    • 14
    • 13
    • 11
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin Alpha2b antibody is un-conjugated
    应用范围
    • 96
    • 39
    • 25
    • 25
    • 18
    • 18
    • 12
    • 12
    • 9
    • 8
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Cow,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b
    亚型
    IgG
    Top Product
    Discover our top product CD41 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Sugiyama, Gamage, Zyla, Armstrong, Advani, Advani, Wang, Lee: "Influenza Virus Infection Induces Platelet-Endothelial Adhesion Which Contributes to Lung Injury." in: Journal of virology, Vol. 90, Issue 4, pp. 1812-23, (2016) (PubMed).

    Araki, Ogawara, Suzuki, Kawai, Watanabe, Ono, Higaki: "Augmented EPR effect by photo-triggered tumor vascular treatment improved therapeutic efficacy of liposomal paclitaxel in mice bearing tumors with low permeable vasculature." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 200, pp. 106-14, (2015) (PubMed).

    Lê, Schneider, Boergeling, Berri, Ducatez, Guerin, Adrian, Errazuriz-Cerda, Frasquilho, Antunes, Lina, Bordet, Jandrot-Perrus, Ludwig, Riteau: "Platelet Activation and Aggregation Promote Lung Inflammation and Influenza Virus Pathogenesis." in: American journal of respiratory and critical care medicine, (2015) (PubMed).

    Mei, Yin, Jin, He, Yin: "The regulatory role of the adrenergic agonists phenylephrine and isoproterenol on fetal hemoglobin expression and erythroid differentiation." in: Endocrinology, Vol. 154, Issue 12, pp. 4640-9, (2013) (PubMed).

  • 抗原
    Integrin Alpha2b (CD41)
    别名
    Integrin alpha 2b/CD41 (CD41 产品)
    别名
    AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
    背景

    Synonyms: CD41, CD41B, GpIIb, AI172977, alphaIIb, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, Itga2b

    Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

    基因ID
    16399
    UniProt
    Q9QUM0
    途径
    Integrin Complex
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