IL17C 抗体 (AA 101-197)
(3 references)-
- 抗原 See all IL17C 抗体
- IL17C (Interleukin 17C (IL17C))
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抗原表位
- AA 101-197
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL17C antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human IL-17C
- 亚型
- IgG
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anti-Interleukin 17C (IL17C) (AA 81-130) antibody
IL17C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17C (IL17C) (AA 1-197) antibodyIL17C 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17C (IL17C) (AA 1-197) antibodyIL17C 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 17C (IL17C) (AA 36-187) antibodyIL17C 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17C (IL17C) (AA 160-172) antibodyVerified IL17C 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 17C (IL17C) (AA 19-197) antibodyIL17C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17C (IL17C) (AA 7-159) antibodyIL17C 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "IL-17C is required for lethal inflammation during systemic fungal infection." in: Cellular & molecular immunology, Vol. 13, Issue 4, pp. 474-83, (2017) (PubMed).
: "IL-17C/IL-17RE Augments T Cell Function in Autoimmune Hepatitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 2, pp. 669-680, (2016) (PubMed).
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: "IL-17C is required for lethal inflammation during systemic fungal infection." in: Cellular & molecular immunology, Vol. 13, Issue 4, pp. 474-83, (2017) (PubMed).
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- 抗原
- IL17C (Interleukin 17C (IL17C))
- 别名
- IL-17C (IL17C 产品)
- 别名
- IL17C antibody, il17-3 antibody, CX2 antibody, IL-17C antibody, IL-21 antibody, interleukin 17C antibody, interleukin 17c antibody, IL17C antibody, il17c antibody, Il17c antibody
- 背景
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Synonyms: CX2, IL-17C, Interleukin-17C, Cytokine CX2, IL17C, UNQ561/PRO1122
Background: Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
- 基因ID
- 27189
- UniProt
- Q9P0M4
- 途径
- Cellular Response to Molecule of Bacterial Origin
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