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Caspase 3 抗体 (AA 11-120)

Name: Caspase 3 抗体 (AA 11-120)
SKU: ABIN747728
Availability: OutOfStock

CASP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded rabbit pancreas labeled with Rabbit Anti pro-caspase-3 Polyclonal Antibody, Unconjugated (ABIN747728) at 1:200 followed by conjugation to the secondary antibody and DAB staining (Caspase 3 抗体 (AA 11-120))

IHC

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti pro-caspase-3 Polyclonal Antibody, Unconjugated (ABIN747728) at 1:200 followed by conjugation to the secondary antibody and DAB staining (Caspase 3 抗体 (AA 11-120))

IHC

Formalin-fixed and paraffin embedded mouse lung labeled with Rabbit Anti pro-caspase-3 Polyclonal Antibody, Unconjugated (ABIN747728) at 1:200 followed by conjugation to the secondary antibody and DAB staining (Caspase 3 抗体 (AA 11-120))

IHC

L1 mouse brain lysates L2 mouse liver lysates probed with Anti pro-caspase-3 Polyclonal Antibody, Unconjugated (ABIN747728) at 1:200 overnight at 4 °C. (Caspase 3 抗体 (AA 11-120))

SDS

Hela cells werefixed with 70% ice-cold methanol overnight at 4℃, 0. (Caspase 3 抗体 (AA 11-120))

Formalin-fixed and paraffin embedded mouse lung labeled with Rabbit Anti pro-caspase-3 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (Caspase 3 抗体 (AA 11-120))

IHC (p)

6 images

(3 references)

产品编号 ABIN747728

发货至: 中国

Datasheet as PDF

抗原 See all Caspase 3 (CASP3) 抗体

Caspase 3 (CASP3)
抗原表位
19

16

16

16

16

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15

13

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12

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9

8

8

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6

6

6

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5

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4

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3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 11-120
适用
254

171

128

17

11

10

9

8

7

5

5

4

3

3

2

2

1

1
人, 小鼠, 大鼠
宿主
257

36

4

2

2
兔
Compatible Secondaries
克隆类型
255

45
多克隆
标记
149

23

20

13

10

6

5

5

5

5

5

5

5

5

5

5

5

5

3

3

3

3

3

2

2

1
This Caspase 3 antibody is un-conjugated
应用范围
226

106

99

83

66

64

47

33

29

27

26

18

10

6

3

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from rat Caspase 3

亚型

IgG

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anti-Caspase 3 (CASP3) (AA 67-175) antibody
CASP3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 220-236), (C-Term) antibody
CASP3 适用: 人 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) antibody
CASP3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 5E1 unconjugated

anti-Caspase 3 (CASP3) (cleaved) antibody
CASP3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (Internal Region) antibody
CASP3 适用: 人, 小鼠, 大鼠, Cow WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (pSer150) antibody
CASP3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 100-200) antibody
CASP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 29-175) antibody
CASP3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 29-175) antibody
CASP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Duan, Li, Li, Xing, Zhang, Li, Zhao, Sun, Gao, Li et al.: "Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic ..." in: Free radical biology & medicine, Vol. 94, pp. 74-87, (2016) (PubMed).

Zhang, Yu: "Matrine inhibits diethylnitrosamine-induced HCC proliferation in rats through inducing apoptosis via p53, Bax-dependent caspase-3 activation pathway and down-regulating MLCK overexpression." in: Iranian journal of pharmaceutical research : IJPR, Vol. 15, Issue 2, pp. 491-9, (2016) (PubMed).

Luo, Chen, Zhang, Chen, Li: "Pharmacokinetics and antitumor efficacy of micelles assembled from multiarmed amphiphilic copolymers with drug conjugates in comparison with drug-encapsulated micelles." in: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, Vol. 98, pp. 9-19, (2015) (PubMed).
抗原

Caspase 3 (CASP3)

别名

Caspase 3 (CASP3 产品)

别名

CPP32 antibody, CPP32B antibody, SCA-1 antibody, A830040C14Rik antibody, AC-3 antibody, Apopain antibody, CC3 antibody, Caspase-3 antibody, Lice antibody, Yama antibody, mldy antibody, xcpp32 antibody, casp3 antibody, zgc:100890 antibody, CASP-3 antibody, caspase-3 antibody, caspase 3 antibody, caspase 3 S homeolog antibody, caspase 3, apoptosis-related cysteine peptidase a antibody, caspase 3, apoptosis-related cysteine peptidase antibody, CASP3 antibody, Casp3 antibody, casp3.S antibody, casp3a antibody

背景

Synonyms: Lice, Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, IRP, Protein Yama, SREBP cleavage activity 1, SCA-1, Casp3, Cpp32
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).

基因ID

25402

UniProt

P55213

途径

Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation