Id2 抗体 (AA 31-134) (Biotin)
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- 抗原 See all Id2 抗体
- Id2 (Inhibitor of DNA Binding 2 (Id2))
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抗原表位
- AA 31-134
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Id2 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Due to the similarity of this protein with ID1, this antibody has a chance to have light cross-reactivity with ID1 due to a 77 % sequence similarity in the range of our immunogen.
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GIG8/ID2
- 亚型
- IgG
- Top Product
- Discover our top product Id2 Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- 别名
- ID2 (Id2 产品)
- 别名
- AI255428 antibody, C78922 antibody, Idb2 antibody, bHLHb26 antibody, Ac2-300 antibody, GIG8 antibody, ID2A antibody, ID2H antibody, XId2 antibody, id2-A antibody, inhibitor of DNA binding 2 antibody, inhibitor of DNA binding 2, HLH protein antibody, inhibitor of DNA binding 2 L homeolog antibody, Id2 antibody, ID2 antibody, id2.L antibody
- 背景
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Synonyms: GIG8, ID2A, ID2H, bHLHb26, DNA-binding protein inhibitor ID-2, Class B basic helix-loop-helix protein 26, Inhibitor of DNA binding 2, Inhibitor of differentiation 2, ID2
Background: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
- 基因ID
- 3398
- UniProt
- Q02363
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