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Smad2/3 抗体 (AA 30-80) (Biotin)

SMAD2/3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN747025
发货至: 中国
  • 抗原 See all Smad2/3 (SMAD2/3) products
    Smad2/3 (SMAD2/3) (Smad2/3 Transcription Factor (SMAD2/3))
    抗原表位
    • 14
    • 11
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-80
    适用
    • 45
    • 33
    • 32
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 43
    • 2
    • 1
    克隆类型
    • 46
    多克隆
    标记
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Smad2/3 antibody is conjugated to Biotin
    应用范围
    • 35
    • 14
    • 13
    • 13
    • 10
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, Pig, 大鼠
    预测反应
    Cow,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Smad2
    亚型
    IgG
  • 应用备注
    WB 1:100-1000
    IHC-P 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    Smad2/3 (SMAD2/3) (Smad2/3 Transcription Factor (SMAD2/3))
    别名
    Smad2/3 (SMAD2/3 产品)
    背景

    Synonyms: Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, SMAD 2, Smad2, hSMAD2, SMAD2, MADH2, MADR2, SMAD2_HUMAN.

    Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

    基因ID
    4087
    UniProt
    Q15796
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