YBX1 抗体 (pSer102)
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- 抗原 See all YBX1 抗体
- YBX1 (Y Box Binding Protein 1 (YBX1))
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抗原表位
- pSer102
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This YBX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody will recognize Y Box-binding protein 3 when phosphorylated at Ser134
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human YB1 around the phosphorylation site of Ser102
- 亚型
- IgG
- Top Product
- Discover our top product YBX1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- YBX1 (Y Box Binding Protein 1 (YBX1))
- 别名
- YB1 (YBX1 产品)
- 别名
- BP-8 antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, MDR-NF1 antibody, NSEP-1 antibody, NSEP1 antibody, YB-1 antibody, YB1 antibody, Byb1 antibody, Cbfa antibody, Dbpb antibody, Ef1a antibody, Msy1 antibody, Nsep1 antibody, Yb1 antibody, bp-8 antibody, csda2 antibody, csdb antibody, dbpb antibody, frgy1 antibody, mdr-nf1 antibody, nsep-1 antibody, nsep1 antibody, yb1 antibody, 1700102N10Rik antibody, C79409 antibody, EF1A antibody, MSY1 antibody, dbpB antibody, mYB-1a antibody, nuclease sensitive element binding protein 1 antibody, Y-box binding protein 1 antibody, Y box binding protein 1 antibody, Y-box binding protein 1 S homeolog antibody, nuclease-sensitive element-binding protein 1 antibody, Y box protein 1 antibody, nsep1 antibody, YBX1 antibody, Ybx1 antibody, ybx1.S antibody, LOC479011 antibody
- 背景
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Synonyms: Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, CBF-A, DNA-binding protein B, DBPB, Enhancer factor I subunit A, EFI-A, Y-box transcription factor, Y-box-binding protein 1, YB-1, YBX1, NSEP1, YB1
Background: Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
- 基因ID
- 4904
- UniProt
- P67809
- 途径
- Regulation of Muscle Cell Differentiation
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