STAT2 抗体 (pTyr690)
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- 抗原 See all STAT2 抗体
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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抗原表位
- pTyr690
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STAT2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This phosphorylation site is homologous to that of Tyr689 in Mouse and Tyr690 in Rat.
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690
- 亚型
- IgG
- Top Product
- Discover our top product STAT2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases." in: PloS one, Vol. 11, Issue 10, pp. e0164080, (2017) (PubMed).
: "
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JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases." in: PloS one, Vol. 11, Issue 10, pp. e0164080, (2017) (PubMed).
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- 抗原
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- 别名
- Stat2 (STAT2 产品)
- 别名
- wu:fj84d07 antibody, p113 antibody, stat2 antibody, 1600010G07Rik antibody, AW496480 antibody, ISGF-3 antibody, P113 antibody, STAT113 antibody, signal transducer and activator of transcription 2 antibody, AGAP000099-PA antibody, stat2 antibody, STAT2 antibody, Stat2 antibody
- 背景
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Synonyms: P113, ISGF-3, STAT113, Signal transducer and activator of transcription 2, STAT2
Background: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- 基因ID
- 6773
- UniProt
- P52630
- 途径
- JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
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